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  1. Forget the Tremor: These Symptoms Come First in Parkinson’s

    Jun 10, 2025 · It often appears alongside other signs like a softer, monotone voice or reduced arm swing while walking — both early signs of extrapyramidal dysfunction.

  2. LAIs Tied to Lower Relapse, Mortality Risk in Schizophrenia

    Oct 16, 2025 · Long-acting injectable antipsychotics are linked to a lower risk for disease relapse and mortality than oral antipsychotics in adults with schizophrenia, a new study shows.

  3. Metoclopramide in the Treatment of Diabetic Gastroparesis

    Acute Dystonic Reactions Acute dystonic reactions are the most frequent extrapyramidal side effects (EPS) from metoclopramide and typically occur within 24–48 h of initiating treatment, …

  4. Novel Drug Safe, Effective for Acute Schizophrenia - Medscape

    May 23, 2025 · The novel PDE10A inhibitor CPL'36 offers a new mechanism of action and is both safe and effective for acute exacerbations of schizophrenia, new research suggests.

  5. Untreated Tardive Dyskinesia Hinders Use of Antipsychotics

    Jul 29, 2024 · Tardive dyskinesia, often underdiagnosed and undertreated, hinders patient adherence to antipsychotics, affecting mental health treatment and caregivers' well …

  6. Treatment Considerations for Psychiatric Syndromes Associated …

    Another important consideration is HIV-infected patients' increased sensitivity to antipsychotic-induced extrapyramidal symptoms, thought to be related to the damage to basal ganglia …

  7. 'Impressive' New Data on Novel Schizophrenia Hopeful KarXT

    May 8, 2024 · The novel investigational antipsychotic KarXT was effective and well tolerated in adults with schizophrenia experiencing acute psychosis in a second phase 3 trial.

  8. New Management Approaches for Gastroparesis - Page 4

    It has the advantage of either parenteral (including subcutaneous) or oral dosing, but side effects including extrapyramidal reactions are not uncommon. [43] Tardive dyskinesia represents a ...

  9. Antipsychotics and Akathisia - Medscape

    Dec 29, 2008 · The potential for the development of extrapyramidal side effects is better understood now that atypical antipsychotic medications have been used prospectively and in …

  10. Long-Acting Injectables Curb Schizophrenia Readmission

    Feb 7, 2024 · Patients with schizophrenia discharged on an LAI antipsychotic had significantly lower 30-day psychiatric readmission rates than those sent home with an oral antipsychotic.