GitHub

Fine-tuning sequence-to-expression models on personal genome and transcriptome data

The code base for our work on improving the performance of sequence-to-expression models for making individual-specific gene expression predictions by fine-tuning them on personal genome and ...
BioSpace

Parse Biosciences Announces FFPE-compatible Barcoding Technology for Whole Transcriptome Single Cell Analysis

New method enables single cell discovery from archived tissue samples, expanding access to translational and clinical research SEATTLE--(BUSINESS WIRE)--Parse Biosciences, the leading provider of ...
eLife

Single-cell transcriptome sequencing for opening the blood-brain barrier through specific mode electroacupuncture stimulation

This study presents a valuable finding that the blood-brain barrier (BBB) may be modulated through specific modes of electroacupuncture stimulation. The data were collected and analyzed using a solid ...
C&EN

The Druggable Transcriptome Project: From Chemical Probes to Precision Medicines

Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, 130 Scripps Way, Jupiter, Florida 33458, United States Department of Chemistry, The Scripps ...
Frontiers

Integration of GWAS and transcriptome analysis to identify temperature-dependent genes involved in germination of rapeseed (Brassica napus L.)

Rapeseed (Brassica napus L.) is one of the most important oil crops, which contributes over 13% of total vegetable oil production around the world (Tan et al., 2024). In China, the Yangtze River Basin ...
The Lancet

Single-cell transcriptome-wide Mendelian randomization and colocalization reveals immune-mediated regulatory mechanisms and drug targets for COVID-19

aDepartment of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China bShanghai ...
IEEE

A Manual for Genome and Transcriptome Engineering

Abstract: Genome and transcriptome engineering have emerged as powerful tools in modern biotechnology, driving advancements in precision medicine and novel therapeutics. In this review, we provide a ...