The FDA has begun soliciting feedback to inform the next version of the Prescription Drug User Fee Act. User fees remain ...

A 28-year-old woman was admitted to the hospital because of severe hypoxemia and right heart failure that had been caused by rapidly progressive pulmonary hypertension. A diagnosis was made.

Risdiplam, an oral pre–messenger RNA splicing modifier, is an efficacious treatment for persons with symptomatic spinal muscular atrophy (SMA). The safety and efficacy of risdiplam in ...

Despite their limited experience, medical students and residents are often sought out for health advice by family and friends. In an inequitable health system, these consults may seem essential.

MASLD has become the most common chronic liver disease worldwide. The authors review the features of the disease as well as pharmacotherapies targeting the associated liver and cardiovascular ...

Plague is a high-consequence infectious disease with epidemic potential. Current treatment guidelines are based on weak evidence. We enrolled persons (excluding pregnant persons) in Madagascar who ...

A 39-year-old man presented with a 1-day history of lower abdominal pain. The blood pressure was 203/132 mm Hg. Imaging revealed a retroperitoneal mass inferior to the aortic bifurcation.

The authors review available data on the benefits and risks of testosterone treatment in middle-aged and older men with moderate hypogonadism.

A new Massachusetts law may be the most far-reaching U.S. state legislation aimed at curtailing the influence of private equity in health care. It could serve as a model for other jurisdictions.

“Corporatization” of health care, a process predicted decades ago, now refers to the general trend throughout the industry ...

Though infant mortality has continuously been targeted by health policy agendas, policies tend to place it in an individualistic and narrow frame, failing to consider and address its structural ...