President Trump, 78, pushed Ohio Gov. Mike DeWine to consider installing Ramaswamy in Vance’s open Senate seat earlier this month — but was rebuffed by the governor in favor of Lt. Gov. Jon Husted.

In his first opportunity to address his high-profile departure, Ramaswamy denied he had a falling-out with Elon Musk, the co-creator of DOGE.

We had Bernie Moreno, JD Vance, Vivek Ramaswamy and me ... a black-tie inaugural ball in Washington sponsored by the Ohio Republican Party. “The question is can you bypass the 20 years ...

Ramaswamy, a 39-year-old entrepreneur and 2024 presidential candidate from suburban Columbus, is one of three major Republican candidates for Ohio governor so far.

Vivek Ramaswamy has landed Vice President JD Vance’s top political advisers to guide his soon-to-launch bid for governor in Ohio, a source involved in the planning told NBC News.

With the appointment of Ohio Lt. Gov. Jon Husted to JD Vance’s Senate seat, Ohio has two Republican U.S. Senators for the first time in 18 years. The last time that happened, the senators were George Voinovich and Mike DeWine — Ohio's current governor who, last week, appointed the 57-year-old Husted to the Vance vacancy.

Ramaswamy will reportedly run for Ohio governor in 2026 after leaving the Department of Government Efficiency.

Former Republican presidential candidate Vivek Ramaswamy has expressed interest in the Ohio U.S. Senate seat being vacated by Vice President-elect JD Vance.

NBC News confirmed a report - citing two sources - that Ramaswamy will focus his efforts on a campaign to become the next governor of Ohio.

Former Republican presidential candidate Vivek Ramaswamy has expressed interest in the Ohio U.S. Senate seat that was vacated by Vice President-elect JD Vance, a person with direct knowledge of the biotech entrepreneur's wishes told The Associated Press.

The entrepreneur will continue leading Donald J. Trump’s government efficiency project before turning his attention to a campaign. He has encountered some turbulence with Mr. Trump, and with Elon Musk.