Inositol trisphosphate receptors (IP3Rs) are pivotal Ca²⁺ channels embedded in the membrane of the endoplasmic reticulum. Their activation by inositol 1,4,5-trisphosphate (IP3) and Ca²⁺ gives rise to ...
The homeostasis of cytosolic calcium (Ca2+) is crucial for several physiological functions such as cell motility and neuronal transmission, among others. In this process, the inositol ...
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