In this study, using C. elegans and human cell lines, we characterized the physiological effects of thiol reductive stress. Because thiol antioxidants result in the increased expression of rips‐1 ...

Author Correction: Lactylation-driven FTO targets CDK2 to aggravate microvascular anomalies in diabetic retinopathy ...

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Rare tumor has a huge unmet medical need without standard regimens, calling for novel therapeutic interventions. The National Cancer Center of China identified a threshold of incidence for rare tumor ...

Facundo D. Batista (Chief Editor) Facundo is the Phillip T. and Susan M. Ragon Professor of Microbiology and Immunology at Harvard Medical School, and Associate Director of the Ragon Institute of MGH, ...

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Among various mutation types, loss of heterozygosity (LOH) events have garnered significant attention due to their high frequency, their impact on large portions of the genome, and their crucial role ...

Polyamines have been implicated in a wide range of biological processes, including growth and development in bacteria and animals, but their function in higher plants is unclear. Here we show that the ...

While a large fraction of the plant microbiota is horizontally acquired from the environment, some taxa are stably associated with their host, independently from soil and environmental conditions ...

The centrosome is a membrane-less organelle, which acts as the main organizer of the microtubule (MT) cytoskeleton in most animal cells. Owing to their capacity to grow MT filaments, they orchestrate ...

It was recently shown that cofactors may interact differently with DNA‐bound nuclear receptor heterodimers (Yang et al, 2000). To understand rexinoid action on genes controlled by a PPRE, we analysed ...