Three people have been killed in Israel, according to officials and local media, with both sides saying the strikes will continue.

Israel’s attack on Iran was long in the making – the result of years of meticulous planning by Israel and days of high-stakes talks between Tel Aviv and Washington, officials told CNN.

Israel’s leader and President Trump appeared to bet they can persevere, but other world leaders warned of unintended outcomes in a volatile region.

President Donald Trump's eventful week included securing a preliminary trade deal with China, deploying National Guard troops to Los Angeles, and responding to Israel's strikes on Iran.

Israeli emergency services have said at least two people were killed in the strikes and dozens of people are injured.

Israel's attack on Iran raises questions like whether the US will get involved, how Iran will respond, and if a wider conflict may be triggered.

VATICAN CITY (Reuters) -Pope Leo appealed on Saturday for authorities in Iran and Israel to act with "reason" after recent airstrikes and to pursue dialogue. He told an audience in St. Peter's Basilica he was following the situation with "great concern."

Israel warns "Tehran will burn" if Iran continues firing missiles, while state media say 60 people have been killed in a strike on Iran's capital.