Assistant Professor of Biomedical Engineering Yi Xue works on 2P-FOCUS, a new two-photon microscopy system, in her lab. The system promises novel insights into biological features that were once only ...

A new two-photon fluorescence microscope developed at UC Davis can capture high-speed images of neural activity at cellular resolution thanks to a new adaptive sampling scheme and line illumination.

Intravital brain imaging is a valuable tool for studying neurons, glial cells, and their surroundings in living animals. It allows the investigation of neurological illnesses, therapeutic efficacy, ...

A newly described technology improves the clarity and speed of using two-photon microscopy to image synapses in the live brain. The brain's ability to learn comes from "plasticity," in which neurons ...

Intravital brain imaging is a powerful method for observing neurons, glial cells, and their surrounding environments in living animals. It facilitates the study of neurological diseases, drug efficacy ...

While confocal microscopy uses a pinhole to reject out-of-focus light to generate the optical section, a multi-photon (or 2-photon) microscope uses a pulsed infrared laser to stimulate fluorescence ...

Researchers used a two-photon phosphorescent probe to monitor capillary flux and oxygen in sets of capillaries, obtaining a robust oxygen and flux estimate within each capillary, sufficient to observe ...

Researchers at University of California Davis (UC Davis) have designed a new laser-scanning approach to microscopy that is expected to open doors to brain-imaging in mouse models with improved speed ...