Bacteria are not the sole cause of caries; tooth resistance also plays an instrumental role. Researchers from the University of Zurich demonstrate that mutated genes lead to defects in the tooth ...

Tufts arise during tooth development, and all human teeth contain multiple tufts before they even erupt into the mouth. Many cracks in teeth do not start at the outer surface of the tooth, as has ...

Enamel is the hardest organic tissue found in nature. It has a very complex structure, which is made up of minerals and enamel-specific proteins produced by tooth-exclusive cells called ameloblasts.

BUFFALO, N.Y. — University at Buffalo oral biologist Hyuk-Jae (Edward) Kwon recently published a study examining how the gene KMT2D (also known as MLL4) affects the development of tooth enamel. The ...

A patient with tooth enamel defects helped scientists discover a key aspect of enamel mineralization. The findings may one day help researchers better understand cell behavior and mitochondrial ...

Exposing teeth to excessive fluoride alters calcium signaling, mitochondrial function, and gene expression in the cells forming tooth enamel- a novel explanation for how dental fluorosis, a condition ...

Molar Incisor Hypomineralization (MIH) and related enamel defects represent a significant developmental anomaly affecting dental enamel quality and structure. These defects, generally identified in ...

An innovative gel that forms a layer over teeth and then recruits calcium and phosphate ions from saliva to build new enamel has the potential to change dental treatment. To date, we don't have any ...

Organoids have now been created from stem cells to secrete the proteins that form dental enamel, the substance that protects teeth from damage and decay. A multi-disciplinary team of scientists from ...

Damaged teeth could one day be repaired with "living fillings" created from stem cells, a new study reports. In the lab, researchers induced stem cells to form small, multicellular mini-organs that ...