This article and associated images are based on a poster originally authored by Paulina Chorobik, Maciej B. Olszewski, John Vincent and Kirsty Winn and presented at ELRIG Drug Discovery 2025 in ...
MADISON, Wis.--(BUSINESS WIRE)--A new study demonstrates how the combination of DNA-encoded libraries (DELs) and NanoBRET Target Engagement technology can accelerate early-stage drug discovery.
Engagement of intracellular targets is often critical to drug mechanisms. Establishing a target engagement (TE) profile is an important step in small- molecule drug discovery as well as chemical probe ...