When a vascular injury occurs, platelets in young mice form much smaller blood clots (left) than platelets in old mice (right), where the clot almost blocks the blood vessel. Fluorescence microscopy ...

A team from Würzburg has fundamentally changed our understanding of platelet biology. The researchers demonstrate that the surface protein integrin αIIbβ3 is not only a key molecule in blood clotting, ...

CHAPEL HILL -- New research at the University of North Carolina at Chapel Hill has found that a fatty molecule on the surface of platelet cells is a regulator of blood coagulation. Besides its role in ...

Future Microbiol. 2013;8(11):1431-1451. Platelet GPIIIa, and even the same epitope within this surface protein, are also targets of autoantibodies, which are generated in HIV-infected patients.

Researchers have discovered a distinct, secondary population of platelets that appears with aging and have hyperreactive behavior and unique molecular properties, which could make them easier to ...