Super-resolution microscopy achieves nanometer resolution without traditional ON/OFF switching
Overcoming the resolution limit in a light microscope of around half a wavelength of light (about 250 nanometers) is one of ...
Howard Hughes Medical Institute10y
Janelia group leader Eric Betzig wins Nobel Prize for the development of super-resolved fluorescence microscopy.
stochastic optical reconstruction microscopy (STORM), developed by HHMI investigator Xiaowei Zhuang at Harvard University; stimulated emission depletion (STED) by Stefan Hell at Max Planck; and ...
idw13d
Optical nanoscopy without the ON/OFF
STED and PALM/STORM microscopy, as well as all other super-resolution fluorescence microscopes, provide resolutions of a fraction of the wavelength of light (nanometers). However, to image ...
Nanowerk11mon
STED Microscopy: Revolutionizing Nanoscale Imaging in Biology and Beyond
STED microscopy relies on the selective deactivation of fluorophores ... SMLM techniques, such as PALM and STORM, rely on the precise localization of individual fluorophores over multiple imaging ...