Objective: To report treatment of spasticity in a spinal cord-injured person with intrathecal morphine after the person developed tolerance to intrathecal baclofen. Method: Spasticity in a 36-year-old ...

Objectives: To evaluate the efficacy of intrathecal baclofen (ITB) for upper extremity spastic hypertonia in tetraplegia of spinal origin. Setting: University of Alabama at Birmingham hospital.

Intrathecal drug administration via lumbar puncture and a spinal access port device led to serious complications in a patient receiving experimental therapy for Niemann-Pick type C. In a case report ...

September 14, 2012 — The US Food and Drug Administration (FDA) has approved a new catheter (Ascenda, Medtronic Inc) for use in the delivery of intrathecal baclofen (ITB) therapy. According to the ...

Södertälje, Sweden, 3 March 2004 - AstraZeneca announced today that its long-acting local anaesthetic Naropin® (ropivacaine) 5.0 mg/ml was recommended for approval in all EU member states for a new ...

Panelists discuss how emerging intrathecal gene therapy for older patients with spinal muscular atrophy (SMA) shows modest efficacy with fewer systemic adverse effects than intravenous administration, ...

Bowrey, S., Thompson, J. (2008) Spinal opioids in postoperative pain relief 1: pharmacology. Nursing Times; 104: 30, 26–27. Sarah Bowrey, MSc, RN, is research nurse ...

Use of intrathecal morphine during surgery or labor significantly increases the risk for postoperative nausea and vomiting (PONV), pruritus, and urinary retention, according to a meta-analysis.