Reversible post-translational modification by poly(ADP-ribose) (PAR) regulates chromatin structure, DNA repair and cell fate in response to genotoxic stress. PAR glycohydrolase (PARG) removes PAR ...
The sugar ribose is more quickly phosphorylated compared to other sugars with the same chemical formula but a different shape. This selective phosphorylation could explain how ribose became the sugar ...