The natural RNAi mechanism can be directed by either short interfering RNA (siRNA) or microRNA (miRNA). 1 There are four key steps in the RNAi pathway. When miRNA acts as the guide for RNAi, only a ...

This article is part of a series on viroids. The first, which can be read here, gave an overview of what viroids are and how they replicate. The second article described the plant host range of ...

In a recent study published in Nature Communications, a group of researchers explored how Death Induced by Survival gene Elimination (DISE) through the analysis of ribonucleic acid (RNA)-induced ...

RNA silencing processes result in the sequence-specific degradation of RNA and effective post-transcriptional gene silencing. In the May 17 Science, Hongwei Li and colleagues from the University of ...

Researchers describe a novel form of gene regulation that is altered in bladder cancer, leading to the boosting of a gene pathway that helps the cancer cells survive during rapid growth. The work ...

RNA interference using small interfering RNAs (siRNAs) has become a mainstay of functional gene characterization and has generated over a dozen FDA-approved therapeutics and drugs in late-stage ...

In this Peek Behind the Paper, we learn more about a recently published paper by Joaquin Abugattas-Nuñez Del Prado (Leiden University, The Netherlands; Universidad Peruana Cayetano Heredia, Lima, Perú ...