RNA molecules are an integral part of the human body: In cells, they ensure the transfer of genetic information and regulate the activity of genes. Some even act as catalysts, allowing chemical ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...

Crystal structure of the NHL domain of mouse TRIM71 complexed with a stem-loop structured Trincr1 RNA motif. Detailed interactions between key residues of TRIM71 and Trincr1 RNA are shown in an ...

The modulation of RNA splicing by small molecules has emerged as a promising strategy for treating pathogenic infections, human genetic diseases, and cancer; however, the principles by which splicing ...

Researchers from Carnegie Mellon University have discovered a way to target RNA that could lead to new treatment options for ...

The most recent developments in the field of A-to-I RNA modification, with a special emphasis on the roles of A-to-I in the genesis and progression of cancer. Adenosine-to-inosine (A-to-I) RNA editing ...

Posts from this topic will be added to your daily email digest and your homepage feed. AlphaFold 3 uses the same method as AI image generators to predict how different molecules fit together.

Japan biotech xFOREST Therapeutics is teaming up with a drug discovery solutions provider in a research pact aiming to develop new RNA structure-targeted small molecule therapeutics, including mRNA ...

Within each cell, there is a constant struggle between life-sustaining molecules and molecules that could hasten its demise. For the first time, scientists have created a molecule that can identify ...

This article and associated images are based on a poster originally authored by Adam Buckle, Julia Unsicker and Iain McWilliam and presented at ELRIG Drug Discovery 2025 in affiliation with Arrayjet ...