Dynamic remodeling of the endomembrane system is a core biological process essential for maintaining cellular compartmentalization and homeostasis. Proteins enriched in intrinsically disordered ...

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets ...

Chemidroplet is a chemical tool, that fused the BTB-containing domain to the multivalent DNA binding domain (DBD) and intrinsically disordered regions (IDRs) to readily control the LLPS of these ...

LLPS as a rising molecular entity in the cytoplasm regulates diseases progression via a variety of ways. For example, the relationship between LLPS and cancer can be summarized into six aspects: gene ...

Crystallization is a well-explored natural phenomenon where atoms or molecules arrange themselves into highly organized solid forms called crystals. This phenomenon has been widely utilized across ...

Liquid-liquid phase separation (LLPS) is a peculiar phenomenon that occurs during crystallization. In a new study, a group of researchers from Doshisha University, Japan, have investigated the ...