DNA, the medium of life, is so deeply associated with the biochemical world that considering its nonbiological applications may seem far-fetched. However, for researchers in the 1980s and 1990s ...

A coarse-grained model of the DNA origami lilypad used in the study. The tails hanging down indicate where redox reporters are located. For scale, the diameter of the disk is approximately 80 nm.

Scientists have been studying ways to use synthetic DNA as a building block for smaller and faster devices. DNA has the advantage of being inherently "coded". Each DNA strand is formed of one of four ...

Johns Hopkins engineers have created a new optical tool that could improve cancer imaging. Their approach, called SPECTRA, uses tiny nanoprobes that light up when they attach to aggressive cancer ...

Fluorogenic DNA aptamers produce light only in the correct structural state, enabling programmable molecular logic, biosensing, DNA origami integrity reporting, and reusable mRNA detection through ...

DNA origami and beyond. A) DNA octahedron that inspired development of DNA origami. B) 2D DNA origami (smiley face serves as an example). C) Hollow 3D DNA origami shapes that are folded from 2D ...

To assemble these minuscule structures, researchers first create a scaffold: a long piece of single-stranded DNA with a carefully designed sequence of bases. Then they add hundreds of shorter DNA ...

Researchers have developed a method to program the spatial organization of double-stranded DNA by incorporating Hoogsteen interactions. Researchers at Aarhus University (Denmark) have developed a ...

How reorganizing existing drugs and vaccine components can dramatically alter their potency, selectivity, and even their ...