Stephanie Melchor is a science writer based in Silicon Valley, California. From roundworms to humans, signalling through the Notch protein-receptor family drives embryonic development, cellular ...

Researchers at Karolinska Institutet in Sweden have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously unknown ...

The Notch signaling system links cellular fate to that of its neighbors, driving proliferation, apoptosis, and cell differentiation in metazoans, whereas dysfunction leads to debilitating ...

A paper published in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

Researchers at the Karolinska Institute have used DNA origami to demonstrate how an important cell receptor can be activated in a previously unknown way. The new study provides insight into how the ...

Stem cells are one of the few cell types within the body that have the ability to both self-renew and produce cells that develop into more specialized cell types which eventually built up a functional ...