In a new study published in Nature titled, “Custom CRISPR-Cas9 PAM variants via scalable engineering and machine learning,” researchers from Massachusetts General Hospital (MGH) and Harvard Medical ...

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions—but there is always room for improvement. A new paper by investigators from Mass General Brigham ...

CRISPR gene editing revolutionized the cell and gene therapy (CGT) industry this past decade, but the industry still faces significant bottlenecks and gaps between development and manufacturing that ...

Scientists developed an AI-powered DNA editing method, enabling precise disease modeling and paving the way for advanced next-generation gene therapies. (Nanowerk News) Precise and targeted DNA ...

Prof. Lukas Dow, biochemistry, and his team published a study in Nature on Aug. 16, detailing a new, more specific gene editing tool that they created to study cancer mutations through preclinical ...

Investigators from Mass General Brigham and Beth Israel Deaconess Medical Center have developed STITCHR, a new gene editing tool that can insert therapeutic genes into specific locations without ...

Ask scientists which gene-editing tool is most needed to advance gene therapy, and they'd probably describe a system that's now close to realization in the labs of Samuel Sternberg at Columbia ...

CRISPR is a gene-editing tool that acts like “molecular scissors,” but using it on cancer is complex. The technology’s biggest impact so far is in research labs, helping scientists understand how ...

Investigators have developed STITCHR, a new gene editing tool that can insert therapeutic genes into specific locations without causing unwanted mutations. The system can be formulated completely as ...

3D visualization of the production of a red fluorescent protein in a tadpole. The gene responsible for its production is specifically activated in muscle cells. A research team headed by the ...