Tissue samples from patients can contaminate each other on their way to the histology laboratory, reports a single-hospital study that experts say reveals longstanding issues in pathology processing.

In clinical routine pathology today, detection of protein in intact formalin-fixed, paraffin-embedded tissue is limited to immunohistochemistry, which is semi-quantitative. This study presents a new ...

Expert Rev Proteomics. 2013;10(4):389-400. The authors have been funded, in part, with federal funds under grant 1R21 CA134359 from the NCI Innovative Molecular Analysis Technologies (IMAT) Program, ...

Tissue/cell processing and embedding Tissue slide sectioning H&E staining Special stains including: PAS, ORO, Trichrome, VVG for elastin, Giemsa Sectioning of thick tissue curls or core punches for ...

As technologies and methodologies advance, so do the potential applications for biospecimens. In this article, we explore seven uses of FFPE, ranging from the common to the cutting-edge.

The two main fixation formats used by researchers are formalin fixation followed by paraffin embedding (FFPE) or snap-frozen in liquid nitrogen (referred to as Fresh Frozen or FF). There is less of a ...

Reflex Testing for Germline BRCA1, BRCA2, PALB2, and ATM Mutations in Pancreatic Cancer: Mutation Prevalence and Clinical Outcomes From Two Canadian Research Registries Accurate transcriptional ...