Emphasis on Potential Clinical Applications and Enhancing RNA Sample Quality Researchers are beginning to look at tissue microarrays (TMA) from different perspectives, including one with a strong ...

Most clinical tissue samples are preserved using formalin fixation followed by embedding in paraffin. By some estimates, almost 90% of tissue sections are prepared using this methodology. Although ...

Tissue microarrays combines tens to hundreds of paraffin-embedded tissue cores into a single paraffin block. It is a practical and highly effective technique for high-throughput analyses of various ...

To study tissue samples from multiple patients, researchers use tissue microarrays (TMAs), a technology in which hundreds of tissue cores are arranged on a single glass slide for analysis by ...

The mutation status of the epidermal growth factor receptor (EGFR) as a selection criterion for therapy with EGFR tyrosine kinase inhibitors (TKI’s) in non-small cell lung cancer (NSCLC) No ...

With respect to assay development, quality assurance and, ultimately, clinical adoption, the primary subject of this review, these advantages are critical. Implicit with these advantages, TMAs enable ...