Using a series of more than 1,000 X-ray snapshots of the shapeshifting of enzymes in action, researchers at Stanford University have illuminated one of the great mysteries of life—how enzymes are able ...
When your wounds heal and your liver detoxifies a poison such as histamine you ingested, you can thank the class of enzymes known as copper amine oxidases for their assistance. Identifying the exact ...
Enzymes catalyze the critical chemical reactions that help build and power living organisms. But chemists studying the origin of life on Earth face a vexing question: How did these metabolic reactions ...
Enzymes are regarded as the key to sustainable chemistry. Despite major advances in protein design, creating artificial ...
Lipoxygenases constitute a family of non-heme iron or manganese-dependent enzymes that catalyse the regio- and stereospecific dioxygenation of polyunsaturated fatty acids (PUFAs) to yield hydroperoxy ...
Pericyclic reactions, which involve concerted electron movement and a cyclic transition state, have long been a part of the synthetic chemist’s tool box. But finding enzymes that catalyze such ...
A team has used neutron crystallography to image all of the atoms in a radical intermediate of a copper amine oxidase enzyme. They disclosed previously unknown details, such as precise conformational ...