The first lineage decisions in mammalian embryonic development are made shortly after a wave of transcriptional activation that acts as a wake-up call for the sleeping embryonic genome to claim the ...

Week 3 of pregnancy is a critical stage when the embryo begins to grow rapidly. During this week, cells divide at an ...

Using the fruit fly, scientists have constructed a complete and detailed single-cell map of embryo development. This research will also help scientists pursue questions like how mutations lead to ...

Researchers have used stem cells to develop new human embryolike structures that model the earliest stages of fetal development so realistically that they even secrete hormones that can turn a lab ...

Researchers at the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have shown for the first time that, before they can start developing into egg and sperm cells, the embryonic ...

In the earliest hours after fertilization, an embryo takes its first steps toward becoming a living organism by shedding maternal control and activating its own genetic program. This critical process, ...

Researchers from the Kind Group have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is first formed after fertilization ...

Conditional genetics and single-embryo RNA-seq show that SETDB1 extinguishes the transient, retroelement-driven transcriptional programs of the totipotent two-cell state to facilitate the exit from ...

What happens in the first weeks after a human embryo implants in the uterus has been a black box. Now, biologists have had a chance to study this stage of development in detail for the first time. The ...