The invention that first enabled researchers to see clear images of living cells was the phase-contrast microscope, which won its inventor, Frits Zernike, a Nobel Prize in 1932. Prior to Zernike's ...

To carry out their study, the team developed an orientation-independent-differential interference contrast (OI-DIC) microscopy system combined with a confocal laser scanning microscope capable of ...

The use of high-resolution bright-field microscopy is essential for cellular-scale biological research, but this technique has limitations due to low image contrast. Using dyes on the sample can ...

Researchers at Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) have developed an innovative microscopy technique capable of improving the observation of living cells. The study, ...

Light microscopy is a key tool that scientists use to image cells, organelles, subcellular structures, and molecules such as proteins and nucleic acids. Because visible light leaves biological ...