RNA is key to the dark matter of the genome − scientists are sequencing it to illuminate human health and disease

Researchers are embarking on the RNA equivalent of the Human Genome Project, including sequencing all the chemical ...
BioTechniques

DNA and RNA methylation directly linked for the first time

DNA and RNA methylation, initially thought to operate as distinct pathways, have been shown to interact closely, shifting our understanding of gene regulation. A team of researchers from the ...
Nanowerk

Cytosine in DNA and RNA: Functions, Modifications, and Applications

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...
ZME Science

The “Quite Tiny” RNA Molecule That Could Answer the Question of the Origin of Life

Researchers at the MRC Laboratory of Molecular Biology in Cambridge have discovered a ribozyme that is shockingly small, yet capable of the fundamental steps of self-replication. They call it QT45 — ...

Tiny, 45 base long RNA can make copies of itself

These random molecules were fed a collection of three-base-long RNAs, each linked to a chemical tag. The idea was that if a molecule is capable of ligating one of these short RNA fragments to itself, ...