Chronic kidney disease (CKD) is a public health challenge that affects more than 800 million people worldwide. 1 CKD can be caused by a variety of disease processes. Many causes are difficult to ...

Huntington’s disease (HD) is one of those rare conditions that affects not just the patient but the entire family—medically, emotionally and genetically. This inherited brain disorder causes gradual ...

Santhosh Girirajan receives funding from the National Institutes of Health. Genetic inheritance may sound straightforward: One gene causes one trait or a specific illness. When doctors use genetics, ...

Most cases of immunoglobulin A (IgA) nephropathy are sporadic (or idiopathic), occurring over time for reasons experts don't fully understand. Research suggests that genetic factors are involved in ...

Familial Alzheimer’s disease is a rare, inherited form of Alzheimer’s that usually develops earlier than other forms of the disease. It’s due to specific genetic variants that tend to run in families.

Huntington’s disease is a genetic condition that is inherited in an autosomal dominant pattern. The genetic change that causes Huntington’s disease is a CAG repeat of the huntingtin (HTT) gene, which ...

Computational biologists from the National University of Singapore (NUS) have uncovered how RNA splicing – a crucial process for isoform expression and protein diversity - is regulated across ...