Chronic exposure to hyperglycemia can lead to cellular dysfunction that may become irreversible over time, a process that is termed glucose toxicity. Our perspective about glucose toxicity as it ...

A new study has identified specific cellular machinery that helps brain cells dispose of toxic proteins associated with Alzheimer’s disease. By screening thousands of genes in lab-grown human neurons, ...

Life sciences researchers need a host of tools to develop and test critical disease-treating drugs and therapies, from basic research to final product release. Primary cells, media, and reagents are ...

Researchers at the Indian Institute of Technology Bombay (IIT Bombay) have found that analysing where antibiotics accumulate within the outer layers of liver cells can serve as an early indicator of ...

Targeting OTULIN has proven to eliminate toxic tau proteins in human neurons for the first time, opening a new avenue for treating dementia.

Lung toxicity and fibrosis are caused by inhaling particles, pathogens, and therapeutics. They can also occur following repeated administration of systemic and oral drugs. Any epithelial damage or ...

Water samples from 20 sites were tested using a panel of immortalized human cell lines corresponding to the liver, kidney and brain to measure cytotoxicity. Results show that each control toxin ...