The authors develop a pratical approach to avoid unwanted interactions between pepsin and SLS in dissolution Tier II tests. Hard gelatin capsules are a common solid oral dosage form, but exposure to ...

This paper discusses what causes cross-linking, how cross-linking is addressed with addition of enzymes, and consideration for occasional high results that can be obtained during release testing. A ...

MORRISTOWN, N.J. Oct. 17, 2012– New data presented today at the American Association of Pharmaceutical Sciences Annual Meeting and Exposition show that plant-based capsules made from Hypromellose ...

Numerous therapeutic advantages are offered by sustained-release drugs, which release active pharmaceutical ingredients (APIs) in a gradual manner. However, the QC of such drugs through conventional ...

Engineers filled a glass tube bent like a tuning fork, kept vibrating by a circuit at its resonance frequency, with simulated stomach and intestine contents and passed an over-the-counter time-release ...

When you take a time-release drug, you count on it doing what the package says: release the drug slowly into your bloodstream to provide benefits over the specified period of time. When the drug ...

In vitro-in vivo correlation (IVIVC) models are developed to explore the relationships between in vitro dissolution/release and in vivo absorption profiles. This model relationship facilitates the ...