Two squirts of a nasal spray, and aged mice started remembering things they had forgotten. That is the headline result from a ...

When young donor myeloid cells are transplanted into aging mouse brains, they quickly adopt aging phenotypes. In contrast, old myeloid cells transplanted in young brains take on a more youthful aspect ...

Two squirts of a nasal spray made from stem-cell particles dialed back inflammatory markers of brain aging in middle-aged ...

This review argues that neurodegeneration is shaped not only by toxic protein buildup but also by immune signaling, with ...

Cellular aging is a central feature of neurodegenerative diseases, and microglia, the brain’s resident immune cells, are especially susceptible. Alas, whether this reflects intrinsic wear and tear or ...

(Boston)—As the brain ages, cells in the central nervous system experience metabolic dysfunction and increased oxidative damage. These cellular issues impair the ability to maintain the myelin sheath ...

A significant, long-term reduction in calorie consumption resulted in a slowing of aging in the brain, according to a study of rhesus monkeys recently published in Aging Cell. The study was conducted ...

As we age, we begin to lose the connections that wire up our brains-and neuroscientists aren't sure why. It is increasingly clear, though, that the loss of synapses-the flexible and adaptive relay ...