This review describes a method of analyzing acid–base disorders that incorporates insights from the traditional, bicarbonate-centered model and the Stewart (or strong ion) model (Table 1). 1–6 ...

Antibiotics are among the most frequently prescribed drugs in medicine. Their use, however, is often limited by associated renal toxic effects. The most common manifestation of these toxic effects is ...

Paracrine communication between different parts of the renal tubule is required for the maintenance of systemic acid–base balance, say researchers. “We demonstrate that the kidney regulates acid–base ...

To define "steady-state" chronic hypercapnia in man, we studied 20 patients with stable carbon dioxide tensions from 34 to 103 mm of mercury and with no apparent complicating disorders. The whole-body ...