Atomic Force Microscopy-based SMFS is widely used due to its high force sensitivity and spatial resolution. In this technique, a biomolecule is attached between a surface and an AFM cantilever. As the ...

The application of single-molecule force spectroscopy has revolutionised our understanding of protein folding and intermolecular interactions by allowing the direct interrogation of folding pathways ...

Fluidic force microscopy (FluidFM) is a cutting-edge technique that integrates atomic force microscopy (AFM) with nanofluidics, enabling simultaneous imaging and manipulation of biological samples at ...

When it comes to analyzing living cells, challenging biological samples and thick, multilayer tissue samples require purposefully designed instrumentation. BioAFMs are ideal when it comes to these ...

The precise measurement of thermodynamic and kinetic properties for biomolecules provides the detailed information for a multitude of applications in biochemistry, biosensing, and health care. However ...

Infrared spectroscopy, known for its effectiveness in the quantitative and qualitative analysis of molecules and materials, has been extensively employed across multiple industries for years. 1,2 Its ...

Invented 30 years ago, the atomic force microscope has been a major driver of nanotechnology, ranging from atomic-scale imaging to its latest applications in manipulating individual molecules, ...

Researchers at Kanazawa University report in Biophysics and Physicobiology how to optimize high-speed atomic force microscopy experiments on live cell membranes, so that moving objects like molecules ...