Depending on who you ask, a nuclear agreement between Iran and the United states is either a non-starter or almost a done deal.

Iran and the United States are preparing for a fifth round of negotiations over Tehran’s rapidly advancing nuclear program, with enrichment emerging as the key issue.

As a new round of nuclear negotiations between Iran and the United States is due to begin in Rome, Iranian sources express growing doubts about Washington’s commitment to reaching a fair agreement, citing increasingly rigid American demands and aggressive tactics.

Iranian leader Ayatollah Ali Khamenei expressed doubt about his country's nuclear negotiations with the United States, saying he does not think the talks will come to a result, according to the official Islamic Republic News Agency.

DUBAI, United Arab Emirates (AP) — Iran’s top diplomat warned Thursday that his country would take “special measures in defense of our nuclear facilities” if Israel continues to threaten Tehran’s atomic sites, raising the stakes further ahead of a new round of talks with the United States.

Iran and the United States are preparing for a fifth round of negotiations over Tehran’s rapidly advancing nuclear program, with enrichment emerging as the key issue

West warns Iran not to hit back as Israel launches revenge strikes - UK and US among nations seeking to keep Middle East from all-out war in wake of Israeli airstrikes on military targets with Tehran

"Fundamental differences still exist between us. The US side does not believe in uranium enrichment in Iran. If this is their objective, there would be no agreement," Araghchi said while responding to US officials' recent demands that Tehran completely stop uranium enrichment on its soil.